Revolution Medicines Inc vs Vertex Pharmaceuticals Inc

We do not publish a verdict for Revolution Medicines Inc (RVMD) and Vertex Pharmaceuticals Inc (VRTX) is overvalued.

We publish an intrinsic value for VRTX but not for RVMD, so the two cannot be ranked on price.

Values as of the 22 Sept 2026 close.

Revolution Medicines Inc (RVMD)

No Leak Score yet

Vertex Pharmaceuticals Inc (VRTX)

Discounting its cash flows at 7.4% (average of 3 methods) values the shares at $380.05; the price of $514.99 is 36% above that value, and 82% of that value comes from beyond year five.

Leak Score 65/100 on 9 of 12 signals

MetricRVMDVRTX
VerdictOvervalued
Price$192.86$514.99
Intrinsic value$380.05
Margin of safety-36%
Leak Score65/100 (9/12)
Market cap$41.3B$130.5B
Revenue growth, 5 years14.2%
Operating margin39.5%
Net margin34.7%
Return on equity-79.1%23.5%
Debt to equity0.460.10
P/E30.0x
Forward P/E24.4x
P/B15.8x6.4x

All stocks in Biotechnology