Regeneron Pharmaceuticals Inc vs Royalty Pharma plc

Regeneron Pharmaceuticals Inc (REGN) is overvalued and Royalty Pharma plc (RPRX) is overvalued.

Both trade above our estimate of their intrinsic value. REGN is the closer of the two: -23%, against -49% for RPRX.

Values as of the 22 Sept 2026 close.

Regeneron Pharmaceuticals Inc (REGN)

Discounting its cash flows at 9.1% (average of 3 methods) values the shares at $652.24; the price of $803.90 is 23% above that value, and 76% of that value comes from beyond year five.

Leak Score 42/100 on 10 of 12 signals

Royalty Pharma plc (RPRX)

Discounting its cash flows at 7.7% (average of 3 methods) values the shares at $39.27; the price of $58.52 is 49% above that value, and 80% of that value comes from beyond year five.

Leak Score 34/100 on 7 of 12 signals

MetricREGNRPRX
VerdictOvervaluedOvervalued
Price$803.90$58.52
Intrinsic value$652.24$39.27
Margin of safety-23%-49%
Leak Score42/100 (10/12)34/100 (7/12)
Market cap$82.8B$33.7B
Revenue growth, 5 years11.0%2.3%
Operating margin26.9%62.3%
Net margin27.9%32.1%
Return on equity14.0%12.4%
Debt to equity0.091.31
P/E19.9x31.1x
Forward P/E13.1x10.2x
P/B2.6x3.8x
Dividend yield0.4%1.8%

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