Illumina Inc vs IQVIA Holdings Inc

Illumina Inc (ILMN) is overvalued and IQVIA Holdings Inc (IQV) is overvalued.

Both trade above our estimate of their intrinsic value. IQV is the closer of the two: -54%, against -290% for ILMN.

Values as of the 22 Sept 2026 close.

Illumina Inc (ILMN)

Discounting its cash flows at 11.4% (average of 3 methods) values the shares at $63.42; the price of $247.46 is 290% above that value, and 68% of that value comes from beyond year five.

Leak Score 62/100 on 10 of 12 signals

IQVIA Holdings Inc (IQV)

Discounting its cash flows at 9.4% (average of 3 methods) values the shares at $174.89; the price of $270.09 is 54% above that value, and 74% of that value comes from beyond year five.

Leak Score 50/100 on 10 of 12 signals

MetricILMNIQV
VerdictOvervaluedOvervalued
Price$247.46$270.09
Intrinsic value$63.42$174.89
Margin of safety-290%-54%
Leak Score62/100 (10/12)50/100 (10/12)
Market cap$37.4B$44.5B
Revenue growth, 5 years6.0%7.5%
Operating margin19.9%13.9%
Net margin18.4%8.1%
Return on equity32.4%23.0%
Debt to equity0.892.63
P/E46.1x33.5x
Forward P/E40.7x18.7x
P/B13.2x7.2x

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