Danaher Corp vs Illumina Inc

Danaher Corp (DHR) is overvalued and Illumina Inc (ILMN) is overvalued.

Both trade above our estimate of their intrinsic value. DHR is the closer of the two: -137%, against -290% for ILMN.

Values as of the 22 Sept 2026 close.

Danaher Corp (DHR)

Discounting its cash flows at 9.1% (average of 3 methods) values the shares at $93.43; the price of $221.09 is 137% above that value, and 75% of that value comes from beyond year five.

Leak Score 45/100 on 10 of 12 signals

Illumina Inc (ILMN)

Discounting its cash flows at 11.4% (average of 3 methods) values the shares at $63.42; the price of $247.46 is 290% above that value, and 68% of that value comes from beyond year five.

Leak Score 62/100 on 10 of 12 signals

MetricDHRILMN
VerdictOvervaluedOvervalued
Price$221.09$247.46
Intrinsic value$93.43$63.42
Margin of safety-137%-290%
Leak Score45/100 (10/12)62/100 (10/12)
Market cap$155.4B$37.4B
Revenue growth, 5 years2.0%6.0%
Operating margin21.2%19.9%
Net margin16.0%18.4%
Return on equity7.6%32.4%
Debt to equity0.530.89
P/E39.3x46.1x
Forward P/E23.8x40.7x
P/B3.0x13.2x
Dividend yield0.6%

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