Astrazeneca plc vs Johnson & Johnson

Astrazeneca plc (AZN) is slightly undervalued and Johnson & Johnson (JNJ) is overvalued.

Against our estimates of intrinsic value, AZN trades at the wider discount: a margin of safety of +7%, against -32% for JNJ.

Values as of the 22 Sept 2026 close.

Astrazeneca plc (AZN)

Discounting its cash flows at 7.4% (average of 3 methods) values the shares at $180.20; the price of $168.37 is 7% below that value, and 82% of that value comes from beyond year five.

Leak Score 59/100 on 3 of 12 signals

Johnson & Johnson (JNJ)

Discounting its cash flows at 7.1% (average of 3 methods) values the shares at $204.15; the price of $269.19 is 32% above that value, and 83% of that value comes from beyond year five.

Leak Score 50/100 on 9 of 12 signals

MetricAZNJNJ
VerdictSlightly undervaluedOvervalued
Price$168.37$269.19
Intrinsic value$180.20$204.15
Margin of safety+7%-32%
Leak Score59/100 (3/12)50/100 (9/12)
Market cap$261.1B$648.7B
Revenue growth, 5 years16.3%2.7%
Operating margin22.4%27.0%
Net margin17.0%21.5%
Return on equity22.0%25.7%
Debt to equity0.640.58
P/E25.2x31.2x
Forward P/E14.6x21.2x
P/B5.2x7.6x
Dividend yield2.0%2.0%

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