AMGEN Inc vs Merck & Co Inc

AMGEN Inc (AMGN) is slightly overvalued and Merck & Co Inc (MRK) is overvalued.

Both trade above our estimate of their intrinsic value. AMGN is the closer of the two: -11%, against -205% for MRK.

Values as of the 22 Sept 2026 close.

AMGEN Inc (AMGN)

Discounting its cash flows at 7.5% (average of 3 methods) values the shares at $369.87; the price of $410.24 is 11% above that value, and 81% of that value comes from beyond year five.

Leak Score 51/100 on 10 of 12 signals

Merck & Co Inc (MRK)

Discounting its cash flows at 7.1% (average of 3 methods) values the shares at $49.49; the price of $150.91 is 205% above that value, and 82% of that value comes from beyond year five.

Leak Score 40/100 on 9 of 12 signals

MetricAMGNMRK
VerdictSlightly overvaluedOvervalued
Price$410.24$150.91
Intrinsic value$369.87$49.49
Margin of safety-11%-205%
Leak Score51/100 (10/12)40/100 (9/12)
Market cap$221.8B$372.3B
Revenue growth, 5 years7.8%9.3%
Operating margin33.3%18.8%
Net margin22.9%4.8%
Return on equity91.5%7.0%
Debt to equity4.901.29
P/E25.5x120.6x
Forward P/E16.8x15.8x
P/B19.0x8.9x
Dividend yield2.5%2.3%

All stocks in Drug Manufacturers - General