Abbvie Inc vs Astrazeneca plc

Abbvie Inc (ABBV) is overvalued and Astrazeneca plc (AZN) is slightly undervalued.

Against our estimates of intrinsic value, AZN trades at the wider discount: a margin of safety of +7%, against -148% for ABBV.

Values as of the 22 Sept 2026 close.

Abbvie Inc (ABBV)

Discounting its cash flows at 7.1% (average of 3 methods) values the shares at $106.86; the price of $265.21 is 148% above that value, and 83% of that value comes from beyond year five.

Leak Score 57/100 on 8 of 12 signals

Astrazeneca plc (AZN)

Discounting its cash flows at 7.4% (average of 3 methods) values the shares at $180.20; the price of $168.37 is 7% below that value, and 82% of that value comes from beyond year five.

Leak Score 59/100 on 3 of 12 signals

MetricABBVAZN
VerdictOvervaluedSlightly undervalued
Price$265.21$168.37
Intrinsic value$106.86$180.20
Margin of safety-148%+7%
Leak Score57/100 (8/12)59/100 (3/12)
Market cap$468.7B$261.1B
Revenue growth, 5 years6.0%16.3%
Operating margin34.2%22.4%
Net margin9.7%17.0%
Return on equity15221.8%22.0%
Debt to equity0.64
P/E75.0x25.2x
Forward P/E16.2x14.6x
P/B5.2x
Dividend yield2.6%2.0%

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